Involvement of DNA methylation in regulating rat <i>Prop1</i> gene expression during pituitary organogenesis
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Involvement of DNA methylation in regulating rat Prop1 gene expression during pituitary organogenesis
PROP1 is a pituitary specific transcription factor that plays a crucial role in pituitary organogenesis. The Prop1 shows varied expression patterns that promptly emerge and then fade during the early embryonic period. However, the regulatory mechanisms governing Prop1 expression remain unclear. Here, we investigated whether Prop1 was under epigenetic regulation by DNA methylation. Bisulfite seq...
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ژورنال
عنوان ژورنال: Journal of Reproduction and Development
سال: 2017
ISSN: 0916-8818,1348-4400
DOI: 10.1262/jrd.2016-102